Peripheral arterial disease


Peripheral arterial disease arises when there is significant narrowing of arteries distal to the arch of the aorta. Narrowing can arise from atheroma, arteritis, local thrombus formation, or embolisation from the heart, or more central arteries. This review includes treatment options for people with symptoms of reduced blood flow to the leg that are likely to arise from atheroma. These symptoms range from calf pain on exercise (intermittent claudication) to rest pain, skin ulceration, or symptoms of ischaemic necrosis (gangrene) in people with critical limb ischaemia.

Latest citations

Anticoagulants (heparin, low molecular weight heparin and oral anticoagulants) for intermittent claudication. (06 June 2014)

Influence of peripheral vascular calcification on efficiency of screening tests for peripheral arterial occlusive disease in diabetes-a cross-sectional study. (01 May 2014)