Peripheral arterial disease


Peripheral arterial disease arises when there is significant narrowing of arteries distal to the arch of the aorta. Narrowing can arise from atheroma, arteritis, local thrombus formation, or embolisation from the heart, or more central arteries. This review includes treatment options for people with symptoms of reduced blood flow to the leg that are likely to arise from atheroma. These symptoms range from calf pain on exercise (intermittent claudication) to rest pain, skin ulceration, or symptoms of ischaemic necrosis (gangrene) in people with critical limb ischaemia.

Latest citations

A meta-analysis to compare Dacron versus polytetrafluroethylene grafts for above-knee femoropopliteal artery bypass. ( 10 September 2014 )

Effects of extended-release niacin with laropiprant in high-risk patients. ( 15 August 2014 )