Clinical Evidence is one of the world's most authoritative medical resources for informing treatment decisions and improving patient care.
Latest updated reviews
- Heart failure (updated)
- Menopausal symptoms (updated)
- Intimate partner violence (updated)
- Hypertension (updated)
- Obesity (updated)
- UTI in children (updated)
- Cluster headache (updated)
- Thromboembolism (updated)
- Infantile colic (updated)
- Summary of all updates
Editorial
When recommending one pharmacological treatment, a prescriber may be confident of the quality of the evidence on the effectiveness/harms of that chosen drug. But can the same be said when prescribing more than one drug? What if one drug interacts with another? With observed increases in co-morbidities and polypharmacy, informing healthcare professionals on the potential for and consequences of drug–drug interactions is becoming increasingly important. Here, using the potential interaction between clopidogrel and PPIs as an example, we consider the current situation and highlight possible obstacles to developing an evidence base on drug–drug interactions.
Our methods
The systematic reviews in Clinical Evidence result from a rigorous process aimed at ensuring that they are both reliable and relevant to clinical practice.
Learn about our methods.
Drug safety alerts
- The EMEA has suspended marketing of sibutramine because of the increased risk of non-fatal heart attacks and strokes.
(21 January 2010) - MHRA issues drug safety alert on the potential increased risk of Stevens-Johnson syndrome associated with HLA-B*1502 allele in patients of Thai or Han Chinese ethnic origin when treated with phenytoin.
(13 January 2010) - MHRA issues drug safety alert on the potential risk of male breast cancer associated with finasteride.
(03 December 2009)
Consultancy reviews
Palliative care
Our latest review synthesises the evidence for key elements of palliative care: symptom control; communication and transition management and provides practical toolkits.
Smoking cessation
We present a new review on an evidence-based approach to Smoking cessation.
Managing HIV infection
View our systematic reviews on the challenges of managing HIV/AIDS in resource-poor settings.
March 10, 2010
News Feeds & Email Alerts
Clinical Evidence Userguide
