Clinical Evidence is one of the world's most authoritative medical resources for informing treatment decisions and improving patient care.
Latest updated reviews
- Shoulder pain (updated)
- Bulimia nervosa (updated)
- Burning mouth syndrome (updated)
- End-stage renal disease (updated)
- Hyperthyroidism (updated)
- Preventing malaria in travellers (updated)
- Diabetic nephropathy: preventing progression (updated)
- Constipation in adults (updated)
- Epilepsy (partial) (updated)
- Summary of all updates
Editorial
In recent years, estimates of glomerular filtration rate (eGFR) have been used as part of an international classification system to stage people with chronic kidney disease (CKD). Increasingly, eGFR is being automatically calculated alongside routine clinical chemistry, and often the corresponding CKD stage will be reported too. The widespread reporting of eGFR has had the impact of a selective screening program for CKD, but has its use in this way been validated? As Catherine Clase outlines in this month's editorial, while eGFR has an important role in identifying people with early-stage kidney disease, eGFR as a screening tool has a number of limitations.
Our methods
The systematic reviews in Clinical Evidence result from a rigorous process aimed at ensuring that they are both reliable and relevant to clinical practice.
Learn about our methods.
Drug safety alerts
- FDA issues drug safety alert to highlight the risk of severe liver injury associated with leflunomide, and the importance of appropriate patient selection and monitoring to reduce the risk.
(13 July 2010) - FDA issues drug safety alert on the possible increased risk of fractures of the hip, wrist, and spine, associated with the use of proton pump inhibitors.
(25 May 2010) - MHRA isssues drug safety alert on the possible small increased risk of fractures associated with the use of tricyclic antidepressants and SSRIs.
(May 2010)
Consultancy reviews
Palliative care
Our latest review synthesises the evidence for key elements of palliative care: symptom control; communication and transition management and provides practical toolkits.
Smoking cessation
We present a new review on an evidence-based approach to Smoking cessation.
Managing HIV infection
View our systematic reviews on the challenges of managing HIV/AIDS in resource-poor settings.
August 1, 2010
News Feeds & Email Alerts
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