Clinical Evidence is one of the world's most authoritative medical resources for informing treatment decisions and improving patient care.
Latest updated reviews
- Fracture prevention (updated)
- PTSD (updated)
- Hepatitis C (chronic) (updated)
- Asthma in adults (updated)
- Preterm birth (updated)
- Autism (updated)
- Irritable bowel syndrome (updated)
- Candidiasis (vulvovaginal) (updated)
- Primary hypothyroidism (updated)
- Summary of all updates
Editorial
Interpreting trial results to determine which malaria treatment to recommend is difficult, and this presents a challenge to health policy makers. Conventional meta-analyses are of limited help owing to malaria's unique epidemiology – resistance to new drugs is rapid and the effectiveness of treatments varies across the world. However, as David Sinclair, Piero Olliaro, and Paul Garner discuss in our editorial, innovative ways of looking at systematic review data may overcome these difficulties, and make the decision clearer.
Our methods
The systematic reviews in Clinical Evidence result from a rigorous process aimed at ensuring that they are both reliable and relevant to clinical practice.
Learn about our methods.
Drug safety alerts
- The EMEA has suspended marketing of sibutramine because of the increased risk of non-fatal heart attacks and strokes.
(21 January 2010) - MHRA issues drug safety alert on the potential increased risk of Stevens-Johnson syndrome associated with HLA-B*1502 allele in patients of Thai or Han Chinese ethnic origin when treated with phenytoin.
(13 January 2010) - MHRA issues drug safety alert on the potential risk of male breast cancer associated with finasteride.
(03 December 2009)
Consultancy reviews
Palliative care
Our latest review synthesises the evidence for key elements of palliative care: symptom control; communication and transition management and provides practical toolkits.
Smoking cessation
We present a new review on an evidence-based approach to Smoking cessation.
Managing HIV infection
View our systematic reviews on the challenges of managing HIV/AIDS in resource-poor settings.







