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BMJ Clinical Evidence is one of the world's most authoritative medical resources for informing treatment decisions and improving patient care.

Editorial

Is a mild adverse effect of a drug treatment always an undesirable event? Or can an adverse effect be exploited to elicit a beneficial effect in another condition? In our Editorial, we touch on this question using a recent study of amitriptyline in the treatment of diarrhoea-predominant irritable bowel syndrome. As we highlight, the distinction between contributions from beneficial and adverse effect is not always clear.

Read the Editorial

Consultancy reviews

Palliative care

Our latest review synthesises the evidence for key elements of palliative care: symptom control; communication and transition management and provides practical toolkits.

Smoking cessation

We present a new review on an evidence-based approach to Smoking cessation.

Managing HIV infection

View our systematic reviews on the challenges of managing HIV/AIDS in resource-poor settings.